AMAL Therapeutics is a Swiss biotech developing unique therapeutic vaccines and a distinct unit of the Discovery Research organization of the Boehringer Ingelheim group. The company has developed a novel peptide/protein-based immunization technology platform, so-called KISIMA®, with the aim of stimulating the patient’s immune system for effective anti-cancer therapy. AMAL’s lead product, ATP128, is in clinical development for metastatic colorectal cancer since July 2019.
The company is currently seeking a highly motivated candidate covering the functions detailed below, for a permanent position based in Geneva.
AMAL Therapeutics is a Swiss biotech developing unique therapeutic vaccines and a distinct unit of the Discovery Research organization of the Boehringer Ingelheim group. The company has developed a novel peptide/protein-based immunization technology platform, so-called KISIMA®, with the aim of stimulating the patient’s immune system for effective anti-cancer therapy. AMAL’s lead product, ATP128, is in clinical development for metastatic colorectal cancer since July 2019.
The company is currently seeking a highly motivated candidate covering the functions detailed below, for a permanent position based in Geneva.
Key Responsibilities
- Monitor drug substance and drug product stability study execution at CMO&CROs including sample pulls, shipment, and distribution
- Review stability protocols and reports from CMOs and CROs
- Review method SOPs from CMOs and CROS
- Receive and compile stability data from CMO and CROs into internal documentation
- Co-ordinate ad-hoc analytical testing at CROs
- Perform in-house method development and sample testing activities as required
- Support external method development and analytical troubleshooting activities as required
Your profile
- BSc in Life Sciences
- A minimum of 2 years’ experience of Analytical Sciences in industrial biopharmaceutical development of recombinant proteins or viral vectors
- Experience of performing stability studies and good hands-on knowledge of physicochemical analytical testing methods such as HPLC, SDS-PAGE, Western blot, CE-SDS, IEF, subvisible and visible particle methods (e.g. MFI, NTA) as applied to biopharmaceuticals. Knowledge of molecular biological/virological methods such as qPCR, Sanger sequencing and TCID50 would be a plus.
- Critical analytical thinker and ability to integrate and interpret data from multiple analysis
- Good knowledge of GMP as applied to analytical testing and stability studies
- Excellent organization skills and ability to work independently and part of the team
- Excellent English verbal and written communication skills and technical proficiency in the use of computers and business software applications