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PhD student: Cancer associated fibroblast autophagy, metabolism and desmoplasia in colorectal cancer

Universität Bern
Bern
NEW
  • 12/5/2025
  • 100%
  • Employee
  • Unlimited employment

PhD student: Cancer associated fibroblast autophagy, metabolism and desmoplasia in colorectal cancer

In consideration of this we are looking for an enthusiastic and ambitious PhD candidate with an interest in oncology and the tumour microenvironment to examine the role of CAF autophagy and altered metabolism on desmoplasia and tumour behaviour in CRC. The successful candidate will explore this through a variety of in vitro methods across 2D and 3D mono- and co- culture models utilising clinically relevant patient derived specimens. As part of our interdisciplinary team, you will receive a comprehensive training from expertise in autophagy, spatial biology and ECM, metabolism, spatial biology and clinical pathology.

Requirements

We are looking for a candidate with an academic degree (MSc or equivalent) in life sciences or biomedical sciences acceptable for matriculation at a Swiss University (Bologna compatible). Previous technical experience with 2D cell culture models and routine cell and molecular biology techniques is essential. The candidate should be proactive, collaborative, have excellent communication skills and possess an aptitude to work in a team as a well as the initiative to work independently. Prior expertise in programming languages (R, Python) or bioinformatics is an advantage. Fluency in English is a prerequisite. The successful applicant will be enrolled in the Graduate School for Cellular and Biomedical Sciences, University of Bern (www.gcb.unibe.ch).

Application

Please send your CV including a list of publications and description of your professional experience, a short motivational letter with statement of your research interests, a list of 2 references (including contact information) and copies of University diploma transcripts with grades as a single PDF-document by email to Cornelia Mileto (