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Lead Mechatronics Engineer: Next-Generation Live-Cell AFM Nano-Imaging

ETH Zürich
Zurich
NEW
  • 2/3/2026
  • 100%
  • Employee
  • Temporary

Lead Mechatronics Engineer: Next-Generation Live-Cell AFM Nano-Imaging

Lead Mechatronics Engineer: Next-Generation Live-Cell AFM Nano-Imaging

The Laboratory of Molecular Medicine, led by Prof. Yohei Yamauchi, is developing the ViViD-AFM V2.0—a next-generation nano-imaging system. This project focuses on transitioning from academic prototypes to commercial-grade industrial systems while ensuring complete IP independence from legacy V1.0 patents.Please enter text here

Project background

The Laboratory of Molecular Medicine, led by Prof. Yohei Yamauchi, is embarking on a transformative phase of the ViViD-AFM (Virus-View Dual Confocal and Atomic Force Microscopy) project. As we transition from academic prototyping to commercial-grade systems, we are seeking a visionary Lead Mechatronics Engineer to drive the design and development of the V2.0 system in tandem with the Lead Architect. This role is part of a strategic hire focusing on the physical realization of a next-generation high-speed AFM system tailored for biological research.

Job description

The Lead Mechatronics Engineer is responsible for the physical realization and hardware integration of the V2.0 system. This position is a Critical Tandem Hire; your success is inextricably linked to the architectural framework developed simultaneously by the Lead Architect.

Profile
  • Hardware Realization: Translate abstract architectural requirements into functional ViViD-AFM V2.0 mechatronic hardware.
  • Precision Engineering: Design and implement sub-nanometer control systems and high-precision scanning devices.
  • Specialized Mechatronics: Substantial track record in the physical realization of high-speed AFM hardware specifically for soft cell surfaces.
  • Control Systems: Expert-level knowledge of sub-nanometer control systems, exceeding the scope of generic mechatronics.
  • Collaborative Design: Proven ability to work in tight technical tandem with architects to solve complex system integration problems.
  • Academic/Industrial Background: Experience in high-precision scanning mechanisms and a history of research-to-industry transition
  • Technical Synchronization: Work in immediate technical alignment with the Lead Architect to ensure seamless hardware-software-architecture integration.
  • Prototyping: Oversee the transition from early-stage hardware components to a commercial-grade integrated device.
We offer

This position offers a unique bridge between high-level academic research at ETH Zurich and the fast-paced environment of a high-tech startup. You will have the opportunity to lead the architectural development of a system that will redefine nano-imaging. We offer a highly collaborative environment and will support your transition into the spin-off phase. ETH Zurich also provides assistance with permit processes (e.g., B-Permit sponsorship) for international candidates.

Working, teaching and research at ETH Zurich
We value diversity and sustainability
In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish. Sustainability is a core value for us - we are consistently working towards a climate-neutral future.
Curious? So are we.

We look forward to receiving your online application with the following documents:

  • Cover Letter
  • Curriculum Vitae (Must detail extensive leadership experience in precision instrumentation architecture or high-speed AFM hardware.)
  • List of Publications and Patents

Further information about ETH Zurich and the Yamauchi Lab can be found on our Website.

Questions regarding the position should be directed to Prof. Yohei Yamauchi, yohei.yamauchi@pharma.ethz.ch (no applications).

Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.

We would like to point out that the pre-selection is carried out by the responsible recruiters and not by artificial intelligence.

For recruitment services the GTC of ETH Zurich Zurich apply.

About ETH Zürich
ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.